Search on: GIANT CELL TUMOR OF BONE 
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Descriptor English:   Giant Cell Tumor of Bone 
Descriptor Spanish:   Tumor Óseo de Células Gigantes 
Descriptor Portuguese:   Tumor de Células Gigantes do Osso 
Tree Number:   C04.557.450.565.380.380
C04.557.450.565.575.420
Definition English:   A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed) 
Indexing Annotation English:   /blood supply /chem /second /secret /ultrastruct permitted; coord IM with BONE NEOPLASMS (IM) or specific precoord bone/neopl term (IM) or specific bone (IM) + BONE NEOPLASMS (IM); osteoblastoclastoma: coord IM with OSTEOBLASTOMA (IM) + organ/neopl coords (IM)
History Note English:   94 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SC secondary
SE secretion SU surgery
TH therapy US ultrasonography
UL ultrastructure UR urine
VE veterinary VI virology
Record Number:   31441 
Unique Identifier:   D018212 

Occurrence in VHL:
 

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